Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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Regulation Of Biological Process (GO:0050789) Genes Targeted by hsa-mir-1245b-5p in B-CLL Leukemia Haslinger Cluster 9 Table contains all genes in the B-CLL Leukemia Haslinger cluster number 9. If a gene harbors a predicted miRNA binding site by one of the three inference methods it is displayed in the final column: M = Weeder-miRvestigator predicted site, P = PITA predicted site and T = TargetScan predicted site. Entrez ID Symbol Description hsa-mir-1245b-5p GO:0050789 3142 HLX H2.0-like homeobox [Source:HGNC Symbol;Acc:4978] zzz999 Yes 8809 IL18R1 interleukin 18 receptor 1 [Source:HGNC Symbol;Acc:5988] zzz999 Yes 7056 THBD thrombomodulin [Source:HGNC Symbol;Acc:11784] zzz999 Yes 9444 QKI quaking homolog, KH domain RNA binding (mouse) [Source:HGNC Symbol;Acc:21100] T Yes 6846 XCL2 chemokine (C motif) ligand 2 [Source:HGNC Symbol;Acc:10646] zzz999 Yes 7294 TXK TXK tyrosine kinase [Source:HGNC Symbol;Acc:12434] zzz999 Yes 10788 IQGAP2 IQ motif containing GTPase activating protein 2 [Source:HGNC Symbol;Acc:6111] zzz999 Yes 366 AQP9 aquaporin 9 [Source:HGNC Symbol;Acc:643] zzz999 5295 PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) [Source:HGNC Symbol;Acc:8979] zzz999 Yes 940 CD28 CD28 molecule [Source:HGNC Symbol;Acc:1653] T Yes 92106 OXNAD1 oxidoreductase NAD-binding domain containing 1 [Source:HGNC Symbol;Acc:25128] T 4068 SH2D1A SH2 domain containing 1A [Source:HGNC Symbol;Acc:10820] zzz999 Yes 9047 SH2D2A SH2 domain containing 2A [Source:HGNC Symbol;Acc:10821] zzz999 Yes 6653 SORL1 sortilin-related receptor, L(DLR class) A repeats containing [Source:HGNC Symbol;Acc:11185] zzz999 11098 PRSS23 protease, serine, 23 [Source:HGNC Symbol;Acc:14370] zzz999 920 CD4 CD4 molecule [Source:HGNC Symbol;Acc:1678] zzz999 Yes 8843 GPR109B G protein-coupled receptor 109B [Source:HGNC Symbol;Acc:16824] zzz999 Yes 23043 TNIK TRAF2 and NCK interacting kinase [Source:HGNC Symbol;Acc:30765] zzz999 Yes 2015 EMR1 egf-like module containing, mucin-like, hormone receptor-like 1 [Source:HGNC Symbol;Acc:3336] zzz999 Yes 5196 PF4 platelet factor 4 [Source:HGNC Symbol;Acc:8861] zzz999 Yes 4118 MAL mal, T-cell differentiation protein [Source:HGNC Symbol;Acc:6817] zzz999 Yes 50486 G0S2 G0/G1switch 2 [Source:HGNC Symbol;Acc:30229] zzz999 5588 PRKCQ protein kinase C, theta [Source:HGNC Symbol;Acc:9410] T Yes 4502 MT2A metallothionein 2A [Source:HGNC Symbol;Acc:7406] zzz999 Yes 7128 TNFAIP3 tumor necrosis factor, alpha-induced protein 3 [Source:HGNC Symbol;Acc:11896] zzz999 Yes 321 APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 [Source:HGNC Symbol;Acc:579] T Yes 8644 AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [Source:HGNC Symbol;Acc:386] zzz999 9555 H2AFY H2A histone family, member Y [Source:HGNC Symbol;Acc:4740] zzz999 Yes 2204 FCAR Fc fragment of IgA, receptor for [Source:HGNC Symbol;Acc:3608] zzz999 5140 PDE3B phosphodiesterase 3B, cGMP-inhibited [Source:HGNC Symbol;Acc:8779] T Yes 23136 EPB41L3 erythrocyte membrane protein band 4.1-like 3 [Source:HGNC Symbol;Acc:3380] T 5209 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [Source:HGNC Symbol;Acc:8874] zzz999 9249 DHRS3 dehydrogenase/reductase (SDR family) member 3 [Source:HGNC Symbol;Acc:17693] zzz999 3655 ITGA6 integrin, alpha 6 [Source:HGNC Symbol;Acc:6142] zzz999 Yes 1545 CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 [Source:HGNC Symbol;Acc:2597] zzz999 4925 NUCB2 nucleobindin 2 [Source:HGNC Symbol;Acc:8044] zzz999 7127 TNFAIP2 tumor necrosis factor, alpha-induced protein 2 [Source:HGNC Symbol;Acc:11895] zzz999 2149 F2R coagulation factor II (thrombin) receptor [Source:HGNC Symbol;Acc:3537] zzz999 Yes 7378 UPP1 uridine phosphorylase 1 [Source:HGNC Symbol;Acc:12576] zzz999 301 ANXA1 annexin A1 [Source:HGNC Symbol;Acc:533] zzz999 Yes 4300 MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 [Source:HGNC Symbol;Acc:7136] zzz999 Yes 2625 GATA3 GATA binding protein 3 [Source:HGNC Symbol;Acc:4172] P T Yes 29851 ICOS inducible T-cell co-stimulator [Source:HGNC Symbol;Acc:5351] zzz999 Yes 6840 SVIL supervillin [Source:HGNC Symbol;Acc:11480] zzz999 54541 DDIT4 DNA-damage-inducible transcript 4 [Source:HGNC Symbol;Acc:24944] T Yes 9120 SLC16A6 solute carrier family 16, member 6 (monocarboxylic acid transporter 7) [Source:HGNC Symbol;Acc:10927] zzz999 3364 HUS1 HUS1 checkpoint homolog (S. pombe) [Source:HGNC Symbol;Acc:5309] T Yes 271 AMPD2 adenosine monophosphate deaminase 2 [Source:HGNC Symbol;Acc:469] zzz999 3560 IL2RB interleukin 2 receptor, beta [Source:HGNC Symbol;Acc:6009] zzz999 Yes 6604 SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 [Source:HGNC Symbol;Acc:11108] zzz999 Yes 10105 PPIF peptidylprolyl isomerase F [Source:HGNC Symbol;Acc:9259] zzz999 Yes 23484 LEPROTL1 leptin receptor overlapping transcript-like 1 [Source:HGNC Symbol;Acc:6555] zzz999 2069 EREG epiregulin [Source:HGNC Symbol;Acc:3443] zzz999 Yes 5775 PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) [Source:HGNC Symbol;Acc:9656] zzz999 3820 KLRB1 killer cell lectin-like receptor subfamily B, member 1 [Source:HGNC Symbol;Acc:6373] zzz999 Yes 55 ACPP acid phosphatase, prostate [Source:HGNC Symbol;Acc:125] T 8807 IL18RAP interleukin 18 receptor accessory protein [Source:HGNC Symbol;Acc:5989] zzz999 Yes 56253 CRTAM cytotoxic and regulatory T cell molecule [Source:HGNC Symbol;Acc:24313] T Yes 5583 PRKCH protein kinase C, eta [Source:HGNC Symbol;Acc:9403] zzz999 Yes 8514 KCNAB2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 [Source:HGNC Symbol;Acc:6229] zzz999 4675 NAP1L3 nucleosome assembly protein 1-like 3 [Source:HGNC Symbol;Acc:7639] T 87 ACTN1 actinin, alpha 1 [Source:HGNC Symbol;Acc:163] zzz999 Yes 50852 TRAT1 T cell receptor associated transmembrane adaptor 1 [Source:HGNC Symbol;Acc:30698] zzz999 Yes 7097 TLR2 toll-like receptor 2 [Source:HGNC Symbol;Acc:11848] zzz999 Yes 2776 GNAQ guanine nucleotide binding protein (G protein), q polypeptide [Source:HGNC Symbol;Acc:4390] zzz999 Yes 7074 TIAM1 T-cell lymphoma invasion and metastasis 1 [Source:HGNC Symbol;Acc:11805] zzz999 Yes 24144 TFIP11 tuftelin interacting protein 11 [Source:HGNC Symbol;Acc:17165] zzz999 8870 IER3 immediate early response 3 [Source:HGNC Symbol;Acc:5392] zzz999 Yes 4783 NFIL3 nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:7787] zzz999 Yes 3949 LDLR low density lipoprotein receptor [Source:HGNC Symbol;Acc:6547] T 101 zzz999 zzz999 zzz999 6678 SPARC secreted protein, acidic, cysteine-rich (osteonectin) [Source:HGNC Symbol;Acc:11219] T Yes 9517 SPTLC2 serine palmitoyltransferase, long chain base subunit 2 [Source:HGNC Symbol;Acc:11278] zzz999 3824 KLRD1 killer cell lectin-like receptor subfamily D, member 1 [Source:HGNC Symbol;Acc:6378] T Yes 3575 IL7R interleukin 7 receptor [Source:HGNC Symbol;Acc:6024] zzz999 Yes 7525 YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 [Source:HGNC Symbol;Acc:12841] zzz999 Yes 7057 THBS1 thrombospondin 1 [Source:HGNC Symbol;Acc:11785] T Yes 5577 PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta [Source:HGNC Symbol;Acc:9392] zzz999 Yes 4753 NELL2 NEL-like 2 (chicken) [Source:HGNC Symbol;Acc:7751] zzz999 Yes 5473 PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) [Source:HGNC Symbol;Acc:9240] zzz999 Yes 6932 TCF7 transcription factor 7 (T-cell specific, HMG-box) [Source:HGNC Symbol;Acc:11639] T Yes 1230 CCR1 chemokine (C-C motif) receptor 1 [Source:HGNC Symbol;Acc:1602] T Yes 290 ANPEP alanyl (membrane) aminopeptidase [Source:HGNC Symbol;Acc:500] zzz999 23312 DMXL2 Dmx-like 2 [Source:HGNC Symbol;Acc:2938] T 5144 PDE4D phosphodiesterase 4D, cAMP-specific [Source:HGNC Symbol;Acc:8783] T Yes 23108 RAP1GAP2 RAP1 GTPase activating protein 2 [Source:HGNC Symbol;Acc:29176] zzz999 Yes 4900 NRGN neurogranin (protein kinase C substrate, RC3) [Source:HGNC Symbol;Acc:8000] zzz999 Yes 3821 KLRC1 killer cell lectin-like receptor subfamily C, member 1 [Source:HGNC Symbol;Acc:6374] zzz999 Yes 5329 PLAUR plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:9053] zzz999 Yes 1441 CSF3R colony stimulating factor 3 receptor (granulocyte) [Source:HGNC Symbol;Acc:2439] zzz999 Yes 1839 HBEGF heparin-binding EGF-like growth factor [Source:HGNC Symbol;Acc:3059] zzz999 Yes 20 ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 [Source:HGNC Symbol;Acc:32] zzz999 Yes 6775 STAT4 signal transducer and activator of transcription 4 [Source:HGNC Symbol;Acc:11365] zzz999 Yes 7850 IL1R2 interleukin 1 receptor, type II [Source:HGNC Symbol;Acc:5994] zzz999 2495 FTH1 ferritin, heavy polypeptide 1 [Source:HGNC Symbol;Acc:3976] zzz999 Yes 1292 COL6A2 collagen, type VI, alpha 2 [Source:HGNC Symbol;Acc:2212] zzz999 2581 GALC galactosylceramidase [Source:HGNC Symbol;Acc:4115] T 919 CD247 CD247 molecule [Source:HGNC Symbol;Acc:1677] zzz999 Yes 3823 KLRC3 killer cell lectin-like receptor subfamily C, member 3 [Source:HGNC Symbol;Acc:6376] zzz999 28232 SLCO3A1 solute carrier organic anion transporter family, member 3A1 [Source:HGNC Symbol;Acc:10952] zzz999 3812 KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 [Source:HGNC Symbol;Acc:6339] zzz999 Yes 3811 KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 [Source:HGNC Symbol;Acc:6338] zzz999 Yes 10123 ARL4C ADP-ribosylation factor-like 4C [Source:HGNC Symbol;Acc:698] T Yes 9315 C5orf13 chromosome 5 open reading frame 13 [Source:HGNC Symbol;Acc:16834] zzz999 Yes 114548 NLRP3 NLR family, pyrin domain containing 3 [Source:HGNC Symbol;Acc:16400] zzz999 Yes 4094 MAF v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) [Source:HGNC Symbol;Acc:6776] zzz999 Yes

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